My family, and most of my shooting friends all cast. I personally have been for over 40 years, leaning much of what I know from my Dad.
The most popular material for many years has been wheel weights, but the ones made from lead, are hard to find these days.
Keep your work area clean, have lots of ventilation, keep you lead temp, down around 700 degrees.
Don't touch your face, smoke, eat or drink while casting, and you will not expose your self to lead.
The secret to not leading a barrel is bullet fitment, and proper lubrication, or powder coating.
Leading does not occur, from the powder flame melting the base of the bullet, it happens when the flame passes around the edges of the bullet, and passes it, as it move down the barrel. This acts as a blow torch effect, down the sides of the bullet. This is where fitment is so important.
This gets worse, as does accuracy, once it begins, and can be dangerous, if enough lead accumulates to restrict the bore, thus increasing pressures.
In order to stop this, the bullet must fit properly, and be soft enough to bump up as the pressure hits it.
More leading occurs, from a bullet that is too hard than one that is too soft.
Measuring the bore size is step one. A 38 / 357 will usually need a .359 - .360 bullet, a post WW2 colt 45 or 45 acp will need a .452 - .454, with most using the .452 size. 44 special / magnum will be around .430 in most guns, i have loaded for. The pattern here, as you can see is .002 or so over bore size.
Before shooting lead in any gun, carefully remove all copper from the barrel. Copper accumulates in bores, and attracts lead quickly.
A seasoned lead free bore does not require frequent cleaning, and the build up of bullet lub from shooting will help prevent leading. I do not over clean by barrels, once they are seasoned.
Finally leading in barrels is time consuming to remove, but easier, if you know a few tips. A Lewis lead remover is a nice tool for this job, and is probably the best.
Another option if you are cheap like I am, is a Copper Chore Girl pad. (this must be copper.. Test it before you use it) Wrap it around a properly fitting bore brush,and clean your barrel.
Soaking the bore with Kroil, or Ed's Red bore cleaner will help loosen the lead, as the oil will get under the lead.
The above is my experience, and what works for me. Sorry for the long post, and happy shooting.