Just a personal observation. Most game animals are human size or larger. A significant number of people shoot prairie dogs that are the size of a 24 oz soda bottle at ranges equal to larger game animals. The question is not about 'numbers of hunters' , but instead 'a safe distance' . Many times my targets were "hiding behind" the cross hairs. Big game hunters consider a "box of shells" to contain 20 rounds, prairie dog shooters consider the box to be at least a 50 caliber ammo can completely full. It is still just a numbers issue, just the scale changes. The Great Plains are the safest.