The lower receiver on the 15-22 is wider than a standard AR15. This will cause binding issues if you use a standard AR15 safety.
Battle Arms development makes a 15-22 specific Ambi-safety that works well.
BAD-ASS-MP15-22 Ambidextrous Safety | BATTLEARMS?
If you hunt around on the net you might be able to find it cheaper. IIRC, I bought my last one at Brownells for $45
Radian also makes an Ambi-safety and Ambi-charing handle specifically for the 15-22, but they are always out of stock when I check